Viktor Brabec Selected Research

Ruthenium Compounds

1/2016	Photo-induced DNA cleavage and cytotoxicity of a ruthenium(II) arene anticancer complex.
6/2006	DNA binding mode of ruthenium complexes and relationship to tumor cell toxicity.

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Viktor Brabec Research Topics

Disease

113	Neoplasms (Cancer) 05/2024 - 01/2002
11	Ovarian Neoplasms (Ovarian Cancer) 05/2018 - 11/2003
8	Carcinoma (Carcinomatosis) 12/2018 - 04/2008
7	Breast Neoplasms (Breast Cancer) 01/2023 - 03/2014
5	Melanoma (Melanoma, Malignant) 07/2020 - 08/2015
3	Rhabdomyosarcoma 06/2022 - 01/2020
3	Necrosis 01/2019 - 02/2012
2	Phototoxic Dermatitis (Phototoxicity) 12/2023 - 05/2011
2	Colonic Neoplasms (Colon Cancer) 11/2023 - 07/2006
2	Triple Negative Breast Neoplasms 01/2023 - 09/2018
2	Neoplasm Metastasis (Metastasis) 01/2023 - 06/2021
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 03/2016
2	Prostatic Neoplasms (Prostate Cancer) 06/2021 - 11/2020
2	Hypersensitivity (Allergy) 10/2018 - 06/2018
1	B-Cell Lymphoma (Lymphoma, B Cell) 07/2023
1	Body Weight (Weight, Body) 12/2021
1	Lewis Lung Carcinoma 12/2021

Drug/Important Bio-Agent (IBA)

65	Cisplatin (Platino)FDA LinkGeneric 10/2023 - 01/2002
40	DNA (Deoxyribonucleic Acid)IBA 05/2024 - 01/2002
38	PlatinumIBA 07/2023 - 01/2002
31	LigandsIBA 05/2024 - 11/2003
14	ProdrugsIBA 10/2023 - 09/2003
11	RutheniumIBA 11/2022 - 01/2002
11	transplatinIBA 02/2016 - 01/2003
9	MetalsIBA 01/2023 - 01/2002
9	DNA AdductsIBA 03/2014 - 07/2002
8	Antineoplastic Agents (Antineoplastics)IBA 11/2023 - 01/2002
7	Proteins (Proteins, Gene)FDA Link 12/2023 - 11/2003
6	IridiumIBA 02/2024 - 10/2016
6	Oxaliplatin (Eloxatin)FDA LinkGeneric 10/2023 - 12/2007
6	Cytotoxins (Cytolysins)IBA 10/2023 - 06/2007
4	Glutathione (Reduced Glutathione)IBA 01/2020 - 11/2006
4	Carboplatin (JM8)FDA LinkGeneric 10/2018 - 08/2012
4	Platinum Compounds (Compounds, Platinum)IBA 06/2005 - 01/2003
3	Doxorubicin (Adriamycin)FDA LinkGeneric 10/2023 - 08/2011
3	Cytostatic AgentsIBA 01/2022 - 01/2003
3	4-cymene (p-cymene)IBA 01/2019 - 09/2018
2	Mitochondrial DNA (mtDNA)IBA 02/2024 - 11/2023
2	Reactive Oxygen Species (Oxygen Radicals)IBA 11/2023 - 05/2018
2	diphosphoric acid (pyrophosphoric acid)IBA 10/2023 - 10/2017
2	CalciumIBA 04/2023 - 11/2022
2	PhenanthrolinesIBA 01/2023 - 03/2018
2	ThioureaIBA 10/2021 - 07/2012
2	DiaminesIBA 10/2021 - 03/2014
2	coumarinIBA 06/2021 - 01/2019
2	A-Form DNA (A-DNA)IBA 11/2020 - 10/2011
2	CinnamatesIBA 11/2020 - 01/2020
2	hydroxide ionIBA 09/2020 - 12/2008
2	AzidesIBA 07/2020 - 05/2012
2	Actins (F Actin)IBA 07/2020 - 12/2016
2	1,2-cyclohexanediamine (dach)IBA 01/2020 - 02/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 03/2016
2	pyridineIBA 01/2019 - 05/2018
2	bathophenanthrolineIBA 01/2019 - 09/2018
2	Dimethyl Sulfoxide (DMSO)FDA LinkGeneric 12/2018 - 08/2015
2	olaparibIBA 10/2018 - 06/2018
2	Liposomes (Liposome)IBA 10/2018 - 06/2018
2	Drug CombinationsIBA 10/2018 - 06/2018
2	Peptides (Polypeptides)IBA 05/2017 - 09/2015
2	Type I DNA Topoisomerases (Topoisomerase I)IBA 05/2016 - 08/2015
2	Ruthenium CompoundsIBA 01/2016 - 06/2006
2	BBR 3464 (BBR3464)IBA 01/2016 - 12/2002
2	Histone Deacetylases (Histone Deacetylase)IBA 11/2015 - 11/2014
2	AcridinesIBA 08/2015 - 10/2011
2	Benzene (Benzole)IBA 03/2014 - 12/2011
2	methylamine (methylammonium)IBA 09/2013 - 07/2006
2	PicolinesIBA 02/2011 - 11/2003
2	CyclohexylaminesIBA 11/2010 - 07/2006
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 05/2010 - 02/2010
2	PiperazineIBA 06/2007 - 11/2003
2	SulfurIBA 11/2006 - 09/2002
1	benzothiazoleIBA 12/2023
1	Green OrIBA 12/2023
1	Messenger RNA (mRNA)IBA 12/2023
1	AntioxidantsIBA 11/2023
1	Gemcitabine FDA Link 10/2023
1	fludarabineIBA 07/2023
1	PalladiumIBA 07/2023
1	OsmiumIBA 04/2023
1	benzimidazoleIBA 04/2023
1	Diclofenac (SR 38)FDA LinkGeneric 01/2023
1	HexanesIBA 01/2022
1	lonidamineIBA 01/2022
1	pentaneIBA 01/2022
1	IronIBA 01/2022
1	GalliumIBA 01/2022
1	cloxyquinIBA 01/2022
1	EthaneIBA 10/2021
1	Photosensitizing Agents (Photosensitizers)IBA 06/2021
1	AndrogensIBA 06/2021
1	Hormones (Hormone)IBA 06/2021
1	Therapeutic UsesIBA 06/2021
1	Estramustine FDA Link 11/2020
1	Growth Factor ReceptorsIBA 11/2020
1	Oleic Acid (Oleate)IBA 11/2020
1	CalreticulinIBA 09/2020
1	Alkynes (Acetylenes)IBA 07/2020

Therapy/Procedure

11	Drug Therapy (Chemotherapy) 01/2023 - 06/2005
7	Therapeutics 08/2021 - 11/2006
3	Photochemotherapy (Photodynamic Therapy) 12/2023 - 06/2021